HIV Genotype

Test Code

HIV GENOTYPE PANEL 2015(WH)

Includes

RT MUTATIONS
Emtricitabine
Lamivudine
Zidovudine
Didanosine
Tenoflovir
Stavudine
Abacavir
Rilpivirine
Etravirine (ETR)
Efavirenz
Nevirapine
PROTEASE MUTATIONS
Tipranavir
Indinavir (IDV)
Lopinavir Ritonavir
Fosamprenavir
Darunavir
Atazanavir
Nelfinavir

Preferred Specimen

Plasma from two lavender top EDTA tubes

Transport Temperature

Frozen

Methodology
Trugene HIV genotyping assay

Limitations

Routinely, the assay will be performed only on samples that have a viral load higher than 1,000 copies/ml, because the sequencing of samples with viral load lower than 1,000 copies is not consistently successful. If a recent HIV RNA viral load (1-2 weeks) is not available, a viral load test will be ordered and performed before the sample is tested for HIV genotyping. Genotyping of samples with viral load lower than 1,000 copies will be attempted only if specifically requested.

Reference Range

No mutations detected.

Clinical Significance

HIV-1 genotyping assays are recommended for patients who experience treatment failure on their first or subsequent regimen. HIV genotyping should also be considered in patients with primary infection, and in patients with established infections that have not yet been treated.

Performing Laboratory
Test performed at the VA Connecticut Virology Lab
Contact: Dr. David Peaper 203-937-3441

Additional Information
Link to March 2015 Newsletter

Last Updated: January 15, 2016

The CPT Codes provided in this document are based on AMA guidelines and are for informational purposes only. CPT coding is the sole responsibility of the billing party. Please direct any questions regarding coding to the payor being billed. Any Profile/panel component may be ordered separately. Reflex tests are performed at an additional charge.