|
|
| A B C D E F G H I J K L M N O P Q R S T U V W X Y Z # |
Hepatitis B core IGM
Test CodeHEP B CORE AB IgM(WH
Preferred Specimen
Gold top tube
Minimum Volume
0.5mL
Transport Temperature
Refrigerated
Setup Schedule
M - F
Report Available
TAT 1 - 4 days
Reference Range
Negative
Clinical Significance
The test detects both IgG and IgM The presence of anti-HBc antibody indicates current and past HBV infection. This antibody is detectable during the prodromal, acute and early convalescent phases where it exists as IgM. Total anti-HBc is present during the window period (after HBsAg disappears and before HBsAb antibodies appear). It may persist longer than HBsAb and be the only marker for past HBV infection. It is not associated with recovery or immunity. Therefore, in the absence of other HBV markers, total HBc antibody is considered a reliable marker of ongoing infection. It is also an accurate marker of previous HBV infection as it may persist long after HBV exposure. In subclinical asymptomatic HBV, HBsAg may not be detectable, and detection of Total anti-HBc and HBsAb must be relied on as evidence of previous HBV infection.
Results are reported as positive, negative, or borderline. Borderline patients should be retested. Patients who are repeatedly borderline should be further assessed by considering other factors such as the pattern of other HBV markers, clinical status and risk factors.
Results are reported as positive, negative, or borderline. Borderline patients should be retested. Patients who are repeatedly borderline should be further assessed by considering other factors such as the pattern of other HBV markers, clinical status and risk factors.
Performing Laboratory
Test performed at the VA Connecticut Virology Lab
Contact: Dr. David Peaper 203-937-3441
Last Updated: October 28, 2015
