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Vitamin D total
Test CodeVITAMIN D TOTAL
Alias/See Also
Chemistry
Preferred Specimen
Gold Top Tube
Minimum Volume
2 mL
Transport Temperature
Refrigerate
Specimen Stability
Room temperature: 72 hours
Refrigerated (2-8°C): 12 days
Frozen (-20°C or colder): 3 months, if separated
Max freeze/thaw cycles: 4
Refrigerated (2-8°C): 12 days
Frozen (-20°C or colder): 3 months, if separated
Max freeze/thaw cycles: 4
Methodology
Chemiluminescence
Setup Schedule
M-F
Report Available
TAT 1 - 5 days
Reference Range
20 – 50 ng/mL
Vitamin D(ng/mL) Health Status
< 12 Associated with Vitamin D deficiency, leading to rickets in infants/children and osteomalacia in adults.
12 - 20 Generally considered inadequate for both bone and overall health in healthy individuals.
>= 20 Generally considered adequate for bone and overall health in healthy individuals.
> 50 Emerging evidence links potential adverse effects to such levels, particularly > 60 ng/mL.
This assay should not be used to assess Vitamin D levels in patients receiving ergocalciferol 50,000 Units (Vitamin D2)
Vitamin D(ng/mL) Health Status
< 12 Associated with Vitamin D deficiency, leading to rickets in infants/children and osteomalacia in adults.
12 - 20 Generally considered inadequate for both bone and overall health in healthy individuals.
>= 20 Generally considered adequate for bone and overall health in healthy individuals.
> 50 Emerging evidence links potential adverse effects to such levels, particularly > 60 ng/mL.
This assay should not be used to assess Vitamin D levels in patients receiving ergocalciferol 50,000 Units (Vitamin D2)
Clinical Significance
Vitamin D is a fat-soluble steroid prohormone mainly produced photochemically in the skin from 7-dehydrocholestrol. The measurement of vitamin D status provides opportunities for preventive and therapeutic interventions. Vitamin D deficiency is a cause of secondary hyperparathyroidism and diseases resulting in impaired bone metabolism (like rickets, osteoporosis, osteomalacia). Reduced 25-OH vitamin D concentrations in blood (vitamin D insufficiency) have been associated with an increasing risk of many chronic diseases, including common cancers, autoimmune or infectious diseases or cardiovascular problems.
Performing Laboratory
Test performed at West Roxbury Chemistry Lab
Contact: Jonathan Dryjowicz-Burek 857-203-5973
Last Updated: April 10, 2019
