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Vitamin B12
Test CodeVITAMIN B12
Alias/See Also
B12
Preferred Specimen
Gold Top Tube
Minimum Volume
2 mL
Transport Temperature
Refrigerate
Specimen Stability
Room temperature: 3 days
Refrigerated (2-8°C): 7 days
Separate and freeze at -20°C or colder if not tested within 7 days.
Max freeze/thaw cycles: 3
Refrigerated (2-8°C): 7 days
Separate and freeze at -20°C or colder if not tested within 7 days.
Max freeze/thaw cycles: 3
Methodology
Chemiluminescence
Setup Schedule
M-F
Report Available
TAT 1 - 7 days
Reference Range
200 - 900 pg/mL
Levels above 300 or 400 pg/mL are rarely associated with B12 deficiency
induced hematological or neurological disease, respectively. Further
testing is suggested for SYMPTOMATIC patients with B12 level between 100
and 300 pg/mL (hematological abnormalities) and between 100 and 400 pg/mL
(neurological abnormalities).
Levels above 300 or 400 pg/mL are rarely associated with B12 deficiency
induced hematological or neurological disease, respectively. Further
testing is suggested for SYMPTOMATIC patients with B12 level between 100
and 300 pg/mL (hematological abnormalities) and between 100 and 400 pg/mL
(neurological abnormalities).
Clinical Significance
Vitamin B12 is decreased in pernicious anemia, total or partial gastrectomy, malabsorption and certain congenital and biochemical disorders.
Performing Laboratory
Test performed in these BACL Chemistry Labs
Contact: Jonathan Dryjowicz-Burek, West Roxbury 857-203-5973
Alternate contact Diane Robert BR 774-826-2294
Last Updated: April 10, 2019
