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SGPT/ALT
Test CodeSGPT/ALT
Alias/See Also
Chemistry
Preferred Specimen
Light Green Top Tube -Plasma
Minimum Volume
2 mL
Other Acceptable Specimens
Gold Top Tube
Transport Temperature
Refrigerate
Specimen Stability
Room temperature: 3 days
Refrigerated (2-8°C): 7 days
Frozen (-40°C or colder): 60 days
Refrigerated (2-8°C): 7 days
Frozen (-40°C or colder): 60 days
Methodology
UV without P5P
Setup Schedule
Daily
Report Available
TAT 1 day
Reference Range
7.0 - 52.0 IUNITS/L
Clinical Significance
Alanine Aminotransferase (ALT) measurements are particularly useful in the diagnosis and management of certain liver diseases, e.g., viral hepatitis and cirrhosis. ALT activity in tissue is generally much lower than aspartate aminotransferase (AST) activity and is found in highest concentrations in the liver. Significant elevations of ALT occur only in diseases of the liver. ALT is often measured in conjunction with AST to determine whether the source of the AST is the liver or the heart. ALT is normally not elevated in cases of myocardial infarction, i.e., a normal ALT, in conjunction with an elevated AST, tends to suggest cardiac disease. However, slight elevations of ALT may occur if an infarct destroys a very large volume of heart muscle.
Performing Laboratory
Test performed in BACL Chemistry Labs
Contact: Jonathan Dryjowicz-Burek, West Roxbury 857-203-5973
Alternate contact Joseph A. Manzone JP 857-364-5092
Alternate contact Diane Robert BR 774-826-2294
Alternate contact Bhumikaben Patel Bedford 781-687-2976
Last Updated: May 17, 2022
