Prothrombin time with INR

Test Code
PROTIME/INR(LOW ISI)


Alias/See Also
INR
PT
PROTIME
Hematology


Preferred Specimen
Light Blue Top Tube – 3.2% sodium citrate


Transport Temperature
Room temperature


Specimen Stability
Samples good for 24hrs from time of collection in an unopened tube at room temperature. Since storage at refrigerated temps may result in cold activation of factor VII, blue tops when being transported should not be placed directly on ice packs or ice.


Reject Criteria (Eg, hemolysis? Lipemia? Thaw/Other?)
Underdrawn tubes are not acceptable for testing.


Methodology
Photo-optical endpoint/calculation

Setup Schedule
Daily


Report Available
TAT 1 day


Limitations
Monitor warfarin patients based on the INR value only!
INR therapeutic range for patients on oral anticoagulant therapy is 2.0-3.5.
For patients who are not receiving anticoagulant therapy, the INR of 1.1 or lower is considered normal


Reference Range
Test  Reference range
Prothrombin Time (PT) 9.8-13.3 sec
INR  ≤1.1
     Comments:
1. For normal patient who are not on anticoagulation, the INR of 1.1 or lower is considered normal.
2. Therapeutic range for patients on anticoagulant should be between 2.0-3.5                                
 


Clinical Significance
Screening test for abnormalities of coagulation factors that are involved in the extrinsic pathway. Also used to monitor effects of Warfarin therapy and to study patients with hereditary and acquired clotting disorders.


Performing Laboratory
Test performed in BACL Hematology Labs
Contact  West Roxbury: Nolan Raymond 857-203-5980
Alternate contact  Joseph A. Manzone JP 857-364-5092
Alternate contact Diane Robert  Brockton 774-826-2294
Alternate contact Bhumikaben Patel Bedford 781-687-2976


Last Updated: May 19, 2025


The CPT Codes provided in this document are based on AMA guidelines and are for informational purposes only. CPT coding is the sole responsibility of the billing party. Please direct any questions regarding coding to the payor being billed. Any Profile/panel component may be ordered separately. Reflex tests are performed at an additional charge.