Protein, CSF

Message

If CJD is suspected - please contact the Laboratory

Test Code

PROTEIN, CSF

Preferred Specimen

CSF

Minimum Volume

1 mL

Transport Temperature

Refrigerate

Specimen Stability

Room Temperature: 24 hours (20-25°C)
Refrigerated: 6 days (2-8°C)
Frozen: > 1 year (-20°C)

Methodology
Pyrogallol Red

Setup Schedule

Daily

Report Available

TAT 1 day

Reference Range

15 – 40 mg/dL

Clinical Significance

The CSF normally contains less than 1% of the amount of protein present in plasma. Clinical disorders associated with increased CSF protein include traumatic spinal tap, increased blood-CSF permeability due to meningitis or hemorrhage, endocrine/metabolic disorders, drug toxicity, and CSF circulation disorders. Clinical disorders associated with decreased CSF total protein include CSF leakage from dural tear, increased intracranial pressure, removal of CSF, hyperthyroidism and leukemia. Young children (6 months to 2 years) also have decreased CSF total protein.

Performing Laboratory
Test performed in these BACL Chemistry Labs
Contact: Jonathan Dryjowicz-Burek, West Roxbury 857-203-5973
Alternate contace Joseph A. Manzone JP 857-364-5092

Last Updated: April 13, 2023

The CPT Codes provided in this document are based on AMA guidelines and are for informational purposes only. CPT coding is the sole responsibility of the billing party. Please direct any questions regarding coding to the payor being billed. Any Profile/panel component may be ordered separately. Reflex tests are performed at an additional charge.