LD

Test Code

Alias/See Also

Lactate dehyrogenase
Chemistry

Preferred Specimen

Light Green Top Tube -Plasma

Minimum Volume

2 mL

Other Acceptable Specimens

Gold Top Tube

Transport Temperature

Refrigerate

Specimen Stability

Room temperature: 7 days
Refrigerated (2-8°C): 4 days
Frozen (-20°C or colder): 6 weeks

Methodology
The Alinity c Lactate Dehydrogenase assay is an automated clinical chemistry assay.
Lactate dehydrogenase is a hydrogen transfer enzyme that catalyzes the oxidation of L-lactate to pyruvate with the mediation of NAD+ as a hydrogen acceptor.1

Lactate dehydrogenase
L-Lactate	+	NAD⁺		Pyruvate	+	NADH H⁺

Methodology: This method uses the IFCC recommended2, 3, 4 forward reaction - Lactate to Pyruvate
Patient results determined by assays using different manufacturers or methods may not be comparable.

Setup Schedule

Daily

Report Available

TAT 1 day

Reference Range

125 – 243 IUNITS/L

Clinical Significance

Elevations in serum lactate dehydrogenase occur from myocardial infarction, liver disease, pernicious and megaloblastic anemia, pulmonary emboli, malignancies, and muscular dystrophy.

Performing Laboratory
Test performed in these BACL Chemistry Labs
Contact: Jonathan Dryjowicz-Burek, West Roxbury 857-203-5973
Alternate contact Joseph A. Manzone JP 857-364-5092
Alternate contact Bhumikaben Patel Bedford 781-687-2976

Last Updated: December 19, 2025

The CPT Codes provided in this document are based on AMA guidelines and are for informational purposes only. CPT coding is the sole responsibility of the billing party. Please direct any questions regarding coding to the payor being billed. Any Profile/panel component may be ordered separately. Reflex tests are performed at an additional charge.