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| A B C D E F G H I J K L M N O P Q R S T U V W X Y Z # |
Creatinine EGFR panel
Test CodeAlias/See Also
Includes
EGFR calculation
Preferred Specimen
Minimum Volume
Other Acceptable Specimens
Transport Temperature
Specimen Stability
Refrigerated (2-8°C): 7 days
Frozen (-20°C or colder): 3 months
Methodology
Methodology: Kinetic Alkaline Picrate
Setup Schedule
Report Available
Reference Range
Reference Range
| VA BACL Reference Range | mg/dL (Serum/Plasma) | |
|---|---|---|
| Reference Range Male Reference Range Female |
0.60 – 1.30 0.50 - 1.20 |
| VA BACL Reference Range | mL/min |
|---|---|
| eGFR | >60 Canned comments: GFR estimates are less precise at higher GFR levels than at lower levels, and healthcare providers should remain aware of caveats for any estimating equation that may influence the accuracy in an individual person |
| Evaluation comments | Estimated Glomerular Filtration Rate(eGFR) calculated using the 2021 chronic kidney disease-Epidemiology(CKD-EPI) Collaboration creatinine equation. Units of measure are mL/min/1.73 m2. |
eGFR (estimated Glomerular Filtration Rate)
- EGFR (CKD-EPI 2021)
where: Scr = serum creatinine in mg/dL
κ = 0.7 (females) or 0.9 (males)
α = -0.241 (female) or -0.302 (male)
min(Scr/κ, 1) is the minimum of Scr/κ or 1.0
max(Scr/κ, 1) is the maximum of Scr/κ or 1.0
Age (years)
Note: Calculators for checking the accuracy of this calculation are available on this website:
eGFR Calculator | National Kidney Foundation (https://www.kidney.org/professionals/kdoqi/gfr_calculator)
Clinical Significance
SUMMARY AND EXPLANATION OF THE TEST
Creatinine is eliminated from blood by glomerular filtration. Reduced renal function results in an increased serum creatinine concentration. Measurement of serum creatinine is used to diagnose and monitor acute and chronic renal disease, estimate glomerular filtration rate (GFR), or assess the status of renal dialysis patients. Urine creatinine analysis is used to calculate creatinine clearance, confirm completeness of 24 hour collections, or serve as a reference quantity for other analytes, such as in calculation of the albumin/creatinine ratio.1 In 1886 Jaffe developed an assay for creatinine based upon the reaction between creatinine and sodium picrate.2 In 1904 Folin3 used this reaction for the quantitative determination of creatinine in urine. Kinetic procedures based on the observed reaction rates of various substances, including creatinine, with alkaline picrate have been proposed by Fabiny4 and Soldin.5 This improved Jaffe chemistry is a kinetic procedure which does not require deproteinization of the sample and is formulated to reduce the interference of serum proteins.
Performing Laboratory
Test performed in BACL Chemistry Labs
Contact: Jonathan Dryjowicz-Burek, West Roxbury 857-203-5973
Alternate contact Joseph A. Manzone JP 857-364-5092
Last Updated: October 7, 2026
