Chloride

Test Code

CHLORIDE

Alias/See Also

CL, Electrolytes
Chemistry

Preferred Specimen

Light Green Top Tube -Plasma

Minimum Volume

2 mL

Other Acceptable Specimens

Gold Top Tube

Transport Temperature

Refrigerate

Specimen Stability

Room temperature: 7 days
Refrigerated (2-8°C): 7 days
Frozen (-20°C or colder): 1 year

Methodology
Indirect ISE

Setup Schedule

Daily

Report Available

TAT 1 day

Reference Range

100 - 110 mmol/L

Clinical Significance

Serum chloride is the major extracellular anion and counter-balances the major cation, sodium, maintaining electrical neutrality of the body fluids. Two thirds of the total anion concentration in extracellular fluids is chloride and it is significantly involved in maintaining proper hydration and osmotic pressure. Movement of chloride ions across the red blood cell membrane is essential for the transport of biocarbonate ions in response to changing concentrations of carbon dioxide. Chloride measurements are used in the diagnosis and treatment of electrolyte and metabolic disorders such as cystic fibrosis and diabetic acidosis.

Performing Laboratory
Test performed in BACL Chemistry Labs
Contact: Jonathan Dryjowicz-Burek, West Roxbury 857-203-5973
Alternate contact Joseph A. Manzone JP 857-364-5092
Alternate contact Diane Robert BR 774-826-2294
Alternate contact Bhumikaben Patel Bedford 781-687-2976

Last Updated: May 17, 2022

The CPT Codes provided in this document are based on AMA guidelines and are for informational purposes only. CPT coding is the sole responsibility of the billing party. Please direct any questions regarding coding to the payor being billed. Any Profile/panel component may be ordered separately. Reflex tests are performed at an additional charge.