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Carbamazepine
Test CodeCARBAMAZEPINE
Alias/See Also
Tegretol
Chemistry
Chemistry
Preferred Specimen
Plain Red Top Tube
Minimum Volume
2 mL
Transport Temperature
Refrigerate
Specimen Stability
Room temperature: 2 days
Refrigerated (2-8°C): 7 days
Frozen (-20°C or colder): 1 month
Refrigerated (2-8°C): 7 days
Frozen (-20°C or colder): 1 month
Reject Criteria (Eg, hemolysis? Lipemia? Thaw/Other?)
Collected in gel tube
Methodology
EIA
Setup Schedule
Daily
Report Available
TAT 1 day
Reference Range
4.0 - 12.0 ug/mL
Clinical Significance
Clinical Use: Carbamazepine and its metabolite, (10,11- Carbamazepine epoxide), are widely used for control of generalized tonic-clonic, partial-onset, complex and mixed seizure disorders. The metabolism of carbamazepine in epileptic patients has several different pathways that can be altered when the patient is co-medicated with other anticonvulsants and, therefore, its therapeutic level should be monitored along with its metabolite in their free and protein bound states.
Performing Laboratory
Test performed in these BACL Chemistry Labs
Contact: Jonathan Dryjowicz-Burek, West Roxbury 857-203-5973
Alternate contact: Joseph A. Manzone JP 857-364-5092
Last Updated: May 17, 2022