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TSH with HAMA Treatment
MessageThis test is currently only available in Bedford CPRS. If you are a BHS provider and wish to see this test offered in BHS CPRS- please contact the BHS Laboratory.
Testing performed at Quest Diagnostics.
Testing performed at Quest Diagnostics.
Test Code
TSH WITH HAMA TREATMENT(O)
CPT Codes
84443 (x2)
Includes
Ultrasensitive TSH with and without HAMA treatment
Preferred Specimen
2 mL serum
Patient Preparation
Specimen collection after fluorescein dye angiography should be delayed for at least 3 days. For patients on hemodialysis, specimen collection should be delayed for 2 weeks after angiography. According to the assay manufacturer Siemens: samples containing fluorescein can produce falsely depressed values.
Minimum Volume
1.5 mL
Transport Temperature
Room temperature
Specimen Stability
Room temperature: 7 days
Refrigerated: 7 days
Frozen: 28 days
Refrigerated: 7 days
Frozen: 28 days
Methodology
Immunoassay (IA)
Setup Schedule
Set up: Tues-Sat; Report available: 2-3 days
Reference Range
TSH, HAMA Treated | See below |
TSH, Untreated | |
Premature infant (28-36 weeks), 1st week of life | 0.20-27.90 mIU/L |
Term infant (>37 Weeks), serum or cord blood | 1.00-39.00 mIU/L |
1-2 Days | 3.20-34.60 mIU/L |
3-4 Days | 0.7-15.40 mIU/L |
5 Days-4 Weeks | 1.70-9.10 mIU/L |
1-11 Months | 0.80-8.20 mIU/L |
1-19 Years | 0.50-4.30 mIU/L |
≥20 Years | 0.40-4.50 mIU/L |
Pregnancy | |
First Trimester | 0.26-2.66 mIU/L |
Second Trimester | 0.55-2.73 mIU/L |
Third Trimester | 0.43-2.91 mIU/L |
Clinical Significance
Precision in the estimation of TSH is crucial to the follow-up of subjects with thyroid disorders. The preincubation of samples to remove HAMA immunoglobulins provides a way to ensure that an otherwise unsuspected rise or drop in TSH concentration will not be interpreted as either a false positive or false negative.
Last Updated: September 24, 2014