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Yo Antibody Screen with Reflex to Titer and Western Blot
MessageThis test is currently only available in BHS CPRS. If you are a Bedford provider and wish to see this test offered in Bedford CPRS- please contact the Bedford Laboratory.
Testing performed at Quest Diagnostics.
Testing performed at Quest Diagnostics.
Test Code
YO AB PANEL,SERUM(O)
CPT Codes
86255
Includes
If Yo Antibody Screen, IFA is positive, then Yo Antibody, Western Blot will be performed at an additional charge (CPT code(s): 84181).
If Yo Antibody, Western Blot is positive, then Yo Antibody Titer will be performed at an additional charge (CPT code(s): 86256).
If Yo Antibody, Western Blot is positive, then Yo Antibody Titer will be performed at an additional charge (CPT code(s): 86256).
Preferred Specimen
0.5 mL serum
Patient Preparation
Overnight fasting is preferred
Minimum Volume
0.2 mL
Transport Temperature
Room temperature
Specimen Stability
Room temperature: 7 days
Refrigerated: 14 days
Frozen: 21 days
Refrigerated: 14 days
Frozen: 21 days
Methodology
Immunofluorescence Assay (IFA)
FDA Status
This test was developed and its analytical performance characteristics have been determined by Quest Diagnostics. It has not been cleared or approved by the U.S. Food and Drug Administration. The FDA has determined that such clearance or approval is not necessary. This assay has been validated pursuant to the CLIA regulations and is used for clinical purposes.
Setup Schedule
Night Sets up 3 days a week.
Reference Range
| Yo Ab Screen, IFA | Negative |
| Yo Ab, Western Blot | Negative |
| Yo Ab Titer | <1:40 Titer |
Clinical Significance
Purkinje Cell (Yo) antibody is found in approximately half of the patients with paraneoplastic cerebellar degeneration and is associated with ovarian, uterine, and small cell lung carcinomas and Hodgkin’s lymphoma.
Last Updated: August 4, 2015
