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Inflammatory Bowel Disease Differentiation Panel

Message
This test is currently only available in BHS CPRS. If you are a Bedford provider and wish to see this test offered in Bedford CPRS- please contact the Bedford Laboratory.

Testing performed at Quest Diagnostics.


Test Code
INFLAMMATORY BOWEL DISEASE PANEL(Q)


CPT Codes
86021 (x2), 86036, 86671 (x2)

Includes
ANCA Screen with Reflex to ANCA Titer
Myeloperoxidase Antibody (MPO)
Proteinase-3 Antibody
Saccharomyces cerevisiae Antibodies (ASCA) (IgG)
Saccharomyces cerevisiae Antibodies (ASCA) (IgA)

If ANCA Screen is positive, then C-ANCA Titer and/or P-ANCA Titer, and/or atypical P-ANCA Titer will be performed at an additional charge (CPT code(s): 86037 for each titer performed).


Preferred Specimen
2 mL serum


Minimum Volume
1.4 mL


Transport Container
Plastic screw-cap vial


Transport Temperature
Room temperature


Specimen Stability
Room temperature: 7 days
Refrigerated: 14 days
Frozen: 21 days


Reject Criteria (Eg, hemolysis? Lipemia? Thaw/Other?)
Gross hemolysis • Lipemia • Grossly icteric


Methodology
Immunoassay (IA)

Setup Schedule
Set up: Mon-Sat; Report available: 3-5 days


Reference Range
ANCA Screen Negative
  P-ANCA Titer <1:20
  C-ANCA Titer <1:20
  Atypical P-ANCA Titer <1:20

Myeloperoxidase Antibody
<1.0 AI No antibody detected
≥1.0 AI Antibody detected

Proteinase-3 Antibody
<1.0 AI No antibody detected
≥1.0 AI Antibody detected

Saccharomyces cerevisiae Ab (IgG)
≤20.0 U Negative
20.1-29.9 U Equivocal
≥30.0 U Positive

Saccharomyces cerevisiae Ab (IgA)
≤20.0 U Negative
20.1-24.9 U Equivocal
≥25.0 U Positive


Clinical Significance
This panel is useful in the diagnosis of  Inflammatory Bowel diseases and can help to distinguish patients with ulcerative colitis from those with Crohn's Disease.



Last Updated: September 20, 2014


The CPT Codes provided in this document are based on AMA guidelines and are for informational purposes only. CPT coding is the sole responsibility of the billing party. Please direct any questions regarding coding to the payor being billed. Any Profile/panel component may be ordered separately. Reflex tests are performed at an additional charge.