AUTOIMMUNE/PARANEOPLASTIC, CSF(MAYO)

Test Code
ENC2


Preferred Specimen
CSF, Specimen Volume: 4 mL


Minimum Volume
2mL


Transport Container
Preferred: Collection vial number 1


Transport Temperature
Frozen


Specimen Stability
Refrigerated (preferred)  28 days


Ambient                          72 hours


Frozen                            28 days



Reject Criteria (Eg, hemolysis? Lipemia? Thaw/Other?)
Gross hemolysis Reject


Gross lipemia Reject


Gross icterus Reject



Clinical Significance
Evaluating new onset encephalopathy (noninfectious or metabolic) comprising confusional states, psychosis, delirium, memory loss, hallucinations, movement disorders, sensory or motor complaints, seizures, dyssomnias, ataxias, nausea, vomiting, inappropriate antidiuresis, coma, dysautonomias, or hypoventilation using spinal fluid specimens.


Performing Laboratory
Mayo Clinic Laboratories

Additional Information
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Last Updated: October 27, 2026


The CPT Codes provided in this document are based on AMA guidelines and are for informational purposes only. CPT coding is the sole responsibility of the billing party. Please direct any questions regarding coding to the payor being billed. Any Profile/panel component may be ordered separately. Reflex tests are performed at an additional charge.