ABETA 42/40, P-TAU217 EVALUATION(O)

ABETA 42/40, P-TAU217 EVALUATION(O)

2.5 mL total plasma collected in a K2 EDTA (lavender-top) tube split into two equal aliquots

1.2 mL

Quest Diagnostics does not perform this test for individuals under the age of 18. Pre-test and post-test counseling is strongly recommended.

Collect blood into a K2 EDTA (lavender-top) tube and mix by inversion 10 times. Centrifuge to separate plasma from cells within 1 hour of collection. Carefully transfer plasma into 2 separate polypropylene tubes or 2 separate Quest issued polypropylene pour-off/transfer tubes. Do not transfer to conical tubes. Store frozen.

Transport tube (x2)

Frozen

Room temperature: Unacceptable
Refrigerated: 72 hours
Frozen: 28 days

Moderate hemolysis • Gross hemolysis • Specimen collected in a glass, polystyrene, or polycarbonate tube • K3 EDTA tube • K2 EDTA gel separator tube

Mon-Sat

4-6 days

AD-Detect™ ABeta 42/40 and p-tau217 Evaluation, Plasma - Intended use is for Alzheimer's Diagnosis. Independent measurement and interpretation of plasma amyloid ratios (AB42/40) and phosphorylated tau levels (p-tau181 and p-tau217) provide clinically valuable insight into patient risk for development of Alzheimer's disease. However, by combining core AD pathological markers for a single analytical interpretation have been shown to significantly improve predictive performance and accuracy for detecting amyloid positivity and confirming a diagnosis of Alzheimer's disease. The AD-Detect™ ABeta 42/40 and p-tau217 Evaluation, Plasma evaluates a patient's plasma AB42/40 ratios and p-tau217 levels reporting out the likelihood that a symptomatic patient suspected of AD has a High, Indeterminant, or Low likelihood of amyloid pathology consistent with AD. This panel meets established performance criteria for confirming a diagnosis of Alzheimer's disease utilizing plasma biomarkers.