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IGG K/L HLC PAIRS WITH RATIO(O)
Test CodeIGG K/L HLC PAIRS WITH RATIO(O)
Preferred Specimen
Serum. 0.75 mL from Red-top tube or gel-barrier tube
Minimum Volume
0.5 mL
Instructions
Separate serum immediately after coagulation (30 minutes) to prevent hemolysis.
Specimen Stability
Room temperature 14 days
Refrigerated 14 days
Frozen 14 days
Freeze/thaw cycles Stable x3
Reject Criteria (Eg, hemolysis? Lipemia? Thaw/Other?)
Microbially-contaminated specimen; specimen containing particulate matter; lipemic or hemolyzed specimen
Reference Range
• IgG κ (g/L): 4.03−9.78
• IgG λ (g/L): 1.97−5.71
• IgG κ:IgG λ ratio: 0.98−2.75
• IgG λ (g/L): 1.97−5.71
• IgG κ:IgG λ ratio: 0.98−2.75
Clinical Significance
This test is used for the quantitative measurement of human IgG heavy chain and light chain intact immunoglobulin in serum. The IgG HLC ratio can be used when monitoring previously diagnosed IgG multiple myeloma in conjunction with other laboratory tests and clinical evaluations.
Performing Laboratory
LabCorp
Additional Information
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Last Updated: January 5, 2026
