RIVAROXABAN(O)

Test Code

RIVAROXABAN(O)

CPT Codes
92981

Preferred Specimen

1 mL plasma collected in a 3.2% sodium citrate (light blue-top) tube

Patient Preparation
Collect samples 2-4 hours post dose (peak)

Minimum Volume

0.5 mL

Transport Temperature

Frozen

Specimen Stability

Room temperature: Unacceptable
Refrigerated: Unacceptable
Frozen: 28 days

Methodology
Chromogenic

Setup Schedule

Mon, Wed, Fri

Report Available

1-4 days

Reference Range

Dosage	Peak mcg/L(at steady state)	Trough* mcg/L
20 mg qD	182-408	3-153
15 mg qD	180-408	2-161
10 mg qD	91-196	1-38

*The lower limit of detection for this assay is 30 mcg/L. The ranges are based on literature references (see FAQs). Click more information (below).

Clinical Significance

Rivaroxaban - Rivaroxaban is an oral factor Xa inhibitor that is indicated to reduce the risk of stroke and systemic embolism in patients with nonvalvular atrial fibrillation. It is also indicated for the treatment, prophylaxis, or the reduction in the risk of reoccurrence of deep vein thrombosis (DVT) or pulmonary embolism (PE). Rivaroxaban does not need to be monitored routinely, however, exceptions may include determination of failure of therapy vs. poor compliance, or potential dose adjustment required for renal or hepatic dysfunction.

Performing Laboratory
Quest Diagnostics Nichols Institute

Additional Information
More information

Last Updated: May 22, 2025

The CPT Codes provided in this document are based on AMA guidelines and are for informational purposes only. CPT coding is the sole responsibility of the billing party. Please direct any questions regarding coding to the payor being billed. Any Profile/panel component may be ordered separately. Reflex tests are performed at an additional charge.