PHOSPHATIDYLSERINE/PT (IGG,IGM)(O)

Test Code
PHOSPHATIDYLSERINE/PT (IGG,IGM)(O)


Alias/See Also
PHOSPHATIDYLSERINE/PROTHROMBIN AB (IGG,IGM)


CPT Codes
83516x2

Includes
PHOSPHATIDYLSERINE(PS/PT)(IGG)(o)
PHOSPHATIDYLSERINE(PS/PT)(IGM)(o)


Preferred Specimen
1 mL platelet-poor plasma (LB, light blue-top tube, 3.2% sodium citrate), room temperature                                            
 


Minimum Volume
0.5 mL


Other Acceptable Specimens
Serum: Completely fill the Vacutainer and allow the blood to clot in an upright position for at least 30 minutes, but not longer than 1 hour before centrifugation. 
Transfer the serum to a plastic transport tube.


Instructions
Platelet-poor plasma: Centrifuge light blue-top tube 15 minutes at approx. 1500 x g within 60 minutes of collection. 
Using a plastic pipette, remove plasma, taking care to avoid the WBC/platelet buffy layer and place into a plastic vial. 
Centrifuge a second time and transfer platelet-poor plasma into a new plastic vial. Plasma must be free of platelets (<10,000/mcL).                                          
                                                                               
Serum: Completely fill the Vacutainer and allow the blood to clot in an upright position for at least 30 minutes, but not longer than 1 hour before centrifugation. 
Transfer the serum to a plastic transport tube.


Transport Container
Plastic


Transport Temperature
Frozen


Specimen Stability
Room temperature: 7 days
Refrigerated: 30 days
Frozen: 30 days


Reject Criteria (Eg, hemolysis? Lipemia? Thaw/Other?)
Gross hemolysis; Grossly lipemic 


Methodology
Immunoassay (IA)

Setup Schedule
Tues, Thurs, Sat


Report Available
1-3 days


Reference Range
Phosphatidylserine/Prothrombin Ab (IgG) ≤30 U


Phosphatidylserine/Prothrombin Ab (IgM) ≤30 U



Clinical Significance
Phosphatidylserine/Prothrombin (PS/PT) Antibody (IgG, IgM) - Antiphospholipid Syndrome (APS) is an acquired autoimmune thrombophilia characterized by thrombosis (venous and/or arterial or microvascular) and/or pregnancy loss or morbidity in association with persistent positivity of a heterogenous group of autoantibodies known as anti-phospholipid antibodies (APL).


Performing Laboratory
Quest Diagnostics

Additional Information
More information

Last Updated: March 13, 2025


The CPT Codes provided in this document are based on AMA guidelines and are for informational purposes only. CPT coding is the sole responsibility of the billing party. Please direct any questions regarding coding to the payor being billed. Any Profile/panel component may be ordered separately. Reflex tests are performed at an additional charge.