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A B C D E F G H I J K L M N O P Q R S T U V W X Y Z # |
HPV Genotypes 16 and 18, Cervical
Test Code19865
CPT Codes
87625
Preferred Specimen
ThinPrep®: 3 mL of PreservCyt® fluid, or
SurePath™: 2 mL of SurePath™ fluid
SurePath™: 2 mL of SurePath™ fluid
Minimum Volume
ThinPrep®: 1.5 mL
SurePath™:1 mL
SurePath™:1 mL
Instructions
Collect the sample as usual according to the manufacturer's instructions.
Note: SurePath™ pellet is no longer acceptable
Note: SurePath™ pellet is no longer acceptable
Transport Temperature
Room temperature
Specimen Stability
ThinPrep®
Room temperature: 90 days
Refrigerated: 90 days
Frozen: Unacceptable
SurePath™
Room Temperature: 28 days
Refrigerated: 90 days
Frozen: Unacceptable
Room temperature: 90 days
Refrigerated: 90 days
Frozen: Unacceptable
SurePath™
Room Temperature: 28 days
Refrigerated: 90 days
Frozen: Unacceptable
Reject Criteria (Eg, hemolysis? Lipemia? Thaw/Other?)
Cervical swabs in Digene® HC cervical sampler • SurePath™ vial without cervical brush/broom • Swabs • SurePath™ pellet • Samples treated with Acetic Acid • Vaginal sources
Methodology
Real-Time Polymerase Chain Reaction
Setup Schedule
Set up: Tues-Sat; Report available: 1-3 days
Reference Range
HPV 16 | Not detected |
HPV 18 | Not detected |
Clinical Significance
Persistent infection with high-risk HPV types increases a woman's risk for progression to dysplasia or cervical cancer. The rate of progression or degree of risk depends on the HPV type. Of all various high-risk types, HPV Types 16 and 18 cause more than 60-65% of cervical cancers. This test will identify the presence or absence of HPV Type 16 DNA and/or Type 18 DNA. Knowledge of the HPV genotype will help physicians diagnose the type of HPV infection and its risk of developing into dysplasia or cervical cancer.