Aldosterone, 24-Hour Urine with Creatinine

Test Code
UALDOS24


Quest Code
19552


CPT Codes
82088, 82570

Includes
Creatinine

CPT code 81050 may be added at an additional charge for volume measurement


Preferred Specimen
1.5 mL 24-hour urine collected in a 24-hour urine container


Minimum Volume
0.8 mL


Other Acceptable Specimens
Random urine collected in a no preservative container (reference ranges do not apply to random urine samples) • 24-hour urine collected in a 24-hour urine container with 10 g Boric acid


Instructions
Record 24-hour urine volume on test requisition and urine vial. Refrigerate during and after collection.


Transport Container
Transport tube


Transport Temperature
Room temperature


Specimen Stability
Room temperature: 7 days
Refrigerated: 28 days
Frozen: 21 days


Reject Criteria (Eg, hemolysis? Lipemia? Thaw/Other?)
Urine collected with HCl


Methodology
Hydrolysis • Extraction • Liquid Chromatography/Tandem Mass Spectrometry (LC/MS/MS)

FDA Status
This test was developed and its analytical performance characteristics have been determined by Quest Diagnostics. It has not been cleared or approved by the U.S. Food and Drug Administration. This assay has been validated pursuant to the CLIA regulations and is used for clinical purposes.

Setup Schedule
Set up: Sun, Tues; Report available: 4-10 days


Reference Range
Aldosterone, 24-Hour Urine
Random Sodium Diet
Agemcg/24 hours
2-7 years5.7 or less
8-11 years10.2 or less
12-16 years15.6 or less
Adults2.3-21.0
Oral sodium loading test (high salt diet for 3 days): 12 mcg/24 hrs or less*

*Funder JW, Carey RM, Mantero F, et al. The Management of Primary
Aldosteronism: Case Detection, Diagnosis, and Treatment: An Endocrine Society Clinical Practice Guideline. J Clin Endocrinol Metab. 2016; 101:1889-1916

Creatinine, 24-Hour Urine
<3 YearsNot established
3-8 Years0.10-0.80 g/24 h
9-12 Years0.20-1.40 g/24 h
13-17 Years0.40-1.90 g/24 h
>17 Years0.50-2.15 g/24 h


Clinical Significance
Aldosterone is a hormone produced by the adrenal glands. Patients with primary hyperaldosteronism exhibit hypokalemia, hypertension, and low direct renin concentrations.


Performing Laboratory
Quest Diagnostics Nichols Institute-San Juan Capistrano, CA
33608 Ortega Highway
San Juan Capistrano, CA 92675-2042




The CPT Codes provided in this document are based on AMA guidelines and are for informational purposes only. CPT coding is the sole responsibility of the billing party. Please direct any questions regarding coding to the payor being billed. Any Profile/panel component may be ordered separately. Reflex tests are performed at an additional charge.