A B C D E F G H I J K L M N O P Q R S T U V W X Y Z # |
ProBNP NT (NTBNP)
Test CodeLAB4891
Alias/See Also
Brain Natriurectic Peptide
CPT Codes
83880
Preferred Specimen
7 mL plasma (see below)
Transport Container
Preferred: Light green top tube
Acceptable: Lavender top or pink top tube (not acceptable at all locations - call lab for more information)
Acceptable: Lavender top or pink top tube (not acceptable at all locations - call lab for more information)
Transport Temperature
Room temperature
Reference Range
Acute setting:
<301 pg/mL
Age-dependent points for acute heart failure:
<50 years: >450 pg/mL
50-75 years: >900 pg/mL
>75 years: >1800 pg/mL
Values above the age-defined reference range have high positive predictive value for the diagnosis of acute heart failure in the absence of renal failure. Values below 300 pg/mL have a high negative predictive value to exclude acute heart failure. Values between the ranges are indeterminate.
Non-acute setting:
</=124 pg/mL ( Negative)
HF unlikely
Consider other diagnoses.
<75 years with value >/= 125 pg/mL or
>75 years with value >/=450 pg/mL
HF likely
Consider other confounding factors and perform echocardiography to confirm HF diagnosis.
<301 pg/mL
Age-dependent points for acute heart failure:
<50 years: >450 pg/mL
50-75 years: >900 pg/mL
>75 years: >1800 pg/mL
Values above the age-defined reference range have high positive predictive value for the diagnosis of acute heart failure in the absence of renal failure. Values below 300 pg/mL have a high negative predictive value to exclude acute heart failure. Values between the ranges are indeterminate.
Non-acute setting:
</=124 pg/mL ( Negative)
HF unlikely
Consider other diagnoses.
<75 years with value >/= 125 pg/mL or
>75 years with value >/=450 pg/mL
HF likely
Consider other confounding factors and perform echocardiography to confirm HF diagnosis.