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Alpha-Fetoprotein, Tumor Marker (AFPTM)
Test CodeLAB559
Quest Code
237
Alias/See Also
AFPTM
CPT Codes
82105
Preferred Specimen
1 mL serum
Minimum Volume
0.5 mL
Instructions
Administration of STRENSIQ may interfere in certain assays and may falsely elevate values. For patients receiving STRENSIQ, consideration should be given to using alternate methods.
Transport Container
Gold top or Plain red top
Transport Temperature
Room temperature
Specimen Stability
Room temperature: 14 days
Refrigerated: 14 days
Frozen: 45 days
Refrigerated: 14 days
Frozen: 45 days
Reject Criteria (Eg, hemolysis? Lipemia? Thaw/Other?)
Grossly lipemic
Methodology
Immunoassay (IA)
Setup Schedule
8am Mon, tues, wed, thur, fri
Report Available
4 days
Limitations
Patients who have received monoclonal mouse antibodies may have abnormal results. For any patient taking a high dose of biotin, the specimen should be drawn at least eight hours after the last dose.
Reference Range
Males(ng/mL) Females(ng/mL)
0-1 month: 0.5 - 16387.0 0.5 - 18964.0
1-11 months: 0.5 - 28.3 0.5 - 77.0
1-3 years: 0.5 - 7.9 0.5 - 11.1
4 years or greater: <6.1 <6.1
Pediatric range is based on full term neonates, values for premature infants may be higher. Ranges adopted from: SJ Soldin, et al. "Pediatric Reference Ranges." Third ed. AACC press (1999). This test was performed using the Siemens (DPC) chemiluminescent method. Values obtained from different assay methods cannot be used inter- changeably. AFP levels, regardless of value, should not be interpreted as absolute evidence of the presence or absence of disease.
0-1 month: 0.5 - 16387.0 0.5 - 18964.0
1-11 months: 0.5 - 28.3 0.5 - 77.0
1-3 years: 0.5 - 7.9 0.5 - 11.1
4 years or greater: <6.1 <6.1
Pediatric range is based on full term neonates, values for premature infants may be higher. Ranges adopted from: SJ Soldin, et al. "Pediatric Reference Ranges." Third ed. AACC press (1999). This test was performed using the Siemens (DPC) chemiluminescent method. Values obtained from different assay methods cannot be used inter- changeably. AFP levels, regardless of value, should not be interpreted as absolute evidence of the presence or absence of disease.
Clinical Significance
Elevation of serum AFP above values found in healthy individuals occurs in several malignant diseases, most notably nonseminomatous testicular cancer and primary hepatocellular carcinoma. AFP is not recommended as a screening procedure to detect cancer in the general population.
Performing Laboratory
| Quest Diagnostics - South Region |
