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Nortriptyline (Aventyl) (NRTL)
MessageCollect specimen >12 hours after last dose.
Test Code
LAB807
Quest Code
272
Alias/See Also
NRTL
CPT Codes
80299
Preferred Specimen
3 mL serum collected in a red-top tube (no gel)
Patient Preparation
Collect at steady-state trough concentration. Specimen should be collected >12 hours after dose.
Minimum Volume
1.5 mL
Other Acceptable Specimens
Plasma collected in: EDTA (lavender-top) tube, sodium heparin (green-top) tube, or lithium heparin (green-top) tube
Instructions
Do not use gel barrier tubes. Separate from cells as soon as possible after clotting.
Transport Container
Transport tube
Transport Temperature
Room temperature
Specimen Stability
Room temperature: 5 days
Refrigerated: 7 days
Frozen: 30 days
Refrigerated: 7 days
Frozen: 30 days
Reject Criteria (Eg, hemolysis? Lipemia? Thaw/Other?)
Gross hemolysis • Gel barrier/Serum separator tube (SST)
Methodology
Chromatography/Mass Spectrometry
FDA Status
This test was developed and its analytical performance characteristics have been determined by Quest Diagnostics. It has not been cleared or approved by FDA. This assay has been validated pursuant to the CLIA regulations and is used for clinical purposes.
Setup Schedule
Monday-friday
Report Available
4 days
Reference Range
50-150 mcg/L
Clinical Significance
Nortriptyline is a tricyclic antidepressant. Therapeutic drug levels are monitored to assist the physician assessing therapeutic response and to avoid toxicity.
Performing Laboratory
Quest Diagnostics Nichols Institute-Chantilly VA |
14225 Newbrook Drive |
Chantilly , VA 20151-2228 |