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A B C D E F G H I J K L M N O P Q R S T U V W X Y Z # |
Rituxan® Sensitivity (CD20)
Test CodeCD20
Quest Code
10981
CPT Codes
86356
Preferred Specimen
5 mL whole blood or bone marrow collected in a sodium heparin (green-top) tube
Minimum Volume
1 mL
Other Acceptable Specimens
Whole blood or bone marrow collected in: EDTA (lavender-top) tube or ACD solution B (yellow-top) tube • Buffy coat • Fresh (unfixed) tissue • CSF • Tissue biopsy • Body fluid • Pleural fluid
Transport Container
Sodium heparin (green-top) tube
Transport Temperature
Room temperature
Specimen Stability
Room temperature: 72 hours
Refrigerated: Unacceptable
Frozen: Unacceptable
Refrigerated: Unacceptable
Frozen: Unacceptable
Reject Criteria (Eg, hemolysis? Lipemia? Thaw/Other?)
Clotted or fixed sample
Methodology
Flow Cytometry (FC)
FDA Status
This test was developed and its analytical performance characteristics have been determined by Quest Diagnostics. It has not been cleared or approved by the U.S. Food and Drug Administration. This assay has been validated pursuant to the CLIA regulations and is used for clinical purposes.
Setup Schedule
Daily
Report Available
2-3 days
Reference Range
See Laboratory Report
Clinical Significance
CD20 antigen is expressed on the surface of >90% of B-cell Non-Hodgkin's Lymphomas (NHL). Binding to CD20 antigen is necessary for the antitumor effect of Rituxan®.
Performing Laboratory
Quest Diagnostics Nichols Institute-San Juan Capistrano, CA |
33608 Ortega Highway |
San Juan Capistrano, CA 92675-2042 |