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Thyroid Peroxidase and Thyroglobulin Antibodies
Test CodeTHYAB
Quest Code
7260
CPT Codes
86376, 86800
Preferred Specimen
1 mL serum
Patient Preparation
Dietary supplements containing biotin may interfere in assays and may skew results to be either falsely high or falsely low. For patients receiving the recommended daily doses of biotin, draw samples at least 8 hours following the last biotin supplementation. For patients on mega-doses of biotin supplements, draw samples at least 72 hours following the last biotin supplementation.
Instructions
Administration of STRENSIQ may interfere in certain assays and may falsely elevate values. For patients receiving STRENSIQ, consideration should be given to using alternate methods.
Transport Container
Transport tube
Transport Temperature
Room Temperature
Specimen Stability
Room temperature: 7 days
Refrigerated: 7 days
Frozen: 28 days
Refrigerated: 7 days
Frozen: 28 days
Reject Criteria (Eg, hemolysis? Lipemia? Thaw/Other?)
Gross hemolysis • Grossly lipemic
Methodology
Immunoassay (IA)
Reference Range
Thyroid Peroxidase Ab | <9 IU/mL |
Thyroglobulin Ab | ≤1 IU/mL |
Clinical Significance
Measurement of thyroglobulin antibodies and thyroid peroxidase antibodies is useful in the diagnosis and management of a variety of thyroid disorders including autoimmune thyroiditis, Hashimoto's Disease, Graves Disease and certain types of goiter.
Performing Laboratory
Quest Diagnostics LLC |
200 Forest Street 3rd Floor, Suite B |
Marlborough, MA 01752-3023 |