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A B C D E F G H I J K L M N O P Q R S T U V W X Y Z # |
Celiac Disease Diagnostic Panel
Test CodeQCELD
Quest Code
15681
CPT Codes
82784, 86364 (x2), 86258 (x2)
Includes
Tissue Transglutaminase (tTG) Antibodies (IgG, IgA)
Gliadin (Deamidated) Antibody (IgG, IgA)
IgA (Immunoglobulin A)
Gliadin (Deamidated) Antibody (IgG, IgA)
IgA (Immunoglobulin A)
Preferred Specimen
3 mL serum
Minimum Volume
1.5 mL
Transport Container
Transport tube
Transport Temperature
Refrigerated (cold packs)
Specimen Stability
Room temperature: 72 hours
Refrigerated: 7 days
Frozen: 30 days
Refrigerated: 7 days
Frozen: 30 days
Reject Criteria (Eg, hemolysis? Lipemia? Thaw/Other?)
Gross hemolysis • Grossly lipemic
Methodology
See individual tests
Reference Range
Tissue Transglutaminase Antibody, IgG
Tissue Transglutaminase Antibody, IgA
Gliadin (Deamidated) Antibody (IgG)
Gliadin (Deamidated) Antibody (IgA)
IgA (Immunoglobulin A)
<15.0 U/mL | Antibody not detected |
≥15.0 U/mL | Antibody detected |
<15.0 U/mL | Antibody not detected |
≥15.0 U/mL | Antibody detected |
Gliadin (Deamidated) Antibody (IgG)
<15.0 U/mL | Antibody not detected | ||
≥15.0 U/mL | Antibody detected |
<15.0 U/mL | Antibody not detected | ||
≥15.0 U/mL | Antibody detected |
IgA (Immunoglobulin A)
Cord Blood | Not Established |
≤3 months | 5-40 mg/dL |
4-6 months | 7-47 mg/dL |
7-11 months | 12-53 mg/dL |
1 year | 20-73 mg/dL |
2 years | 20-99 mg/dL |
3-5 years | 22-140 mg/dL |
6-8 years | 31-180 mg/dL |
9-11 years | 33-200 mg/dL |
12-16 years | 36-220 mg/dL |
17-60 years | 47-310 mg/dL |
≥61 years | 70-320 mg/dL |
Clinical Significance
Celiac disease is characterized by the presence of Transglutaminase, Gliadin, and Reticulin Antibodies. Such patients display a hypersensitivity to gluten (wheat) in their diet. The antibody is undetectable when patients with hypersensitivity are placed on gluten-free diets. Antibody IgA is more specific and IgG is more sensitive to Celiac disease.
Performing Laboratory
Quest Diagnostics LLC |
200 Forest Street, 3rd Floor, Suite B |
Marlborough, MA 01752-3023 |