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Vitamin B2 (Riboflavin)
Test Code36399
Preferred Specimen
1 mL frozen serum collected in a light protected red-top tube (no gel)
Patient Preparation
Overnight fasting is required. Avoidance of vitamin supplements for 24 hours prior to collection is preferred.
Minimum Volume
0.5 mL
Other Acceptable Specimens
Frozen plasma collected in a light protected EDTA (lavender-top) tube
Instructions
Pour serum or plasma into amber transport tube (preferred) or transport tube wrapped in aluminum foil to protect from light.
Transport Temperature
Frozen
Specimen Stability
Room temperature: Unacceptable
Refrigerated: Unacceptable
Frozen: 30 days
Refrigerated: Unacceptable
Frozen: 30 days
Reject Criteria (Eg, hemolysis? Lipemia? Thaw/Other?)
Serum separator tube
Methodology
Chromatography/Mass Spectrometry
FDA Status
This test was developed and its analytical performance characteristics have been determined by Quest Diagnostics. It has not been cleared or approved by FDA. This assay has been validated pursuant to the CLIA regulations and is used for clinical purposes.
Setup Schedule
Set up: Tues-Sat; Report available: 3-4 days
Reference Range
6.2-39.0 nmol/L
Clinical Significance
Vitamin B2 is involved in metabolism of fats, carbohydrates, and protein. The clinical manifestations of deficiency are non-specific. Clinical manifestations include mucocutaneous lesions of the mouth and skin, corneal vascularization, anemia, and personality changes.
Performing Laboratory
Quest Diagnostics Nichols Institute Valencia
27027 Tourney Road
Valencia, CA 91355-5386