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Neuromyelitis Optica (NMO) Evaluation with Reflex
Test CodeNMOIGG
Alias/See Also
NMO IgG, AQP, AQP4
CPT Codes
86255
Preferred Specimen
2.0 mL of whole blood (1.0 mL of serum)
Minimum Volume
1.0 mL of whole blood (0.5 mL of serum)
Transport Container
Serum Separator (gold top) or No Additive Red Top
Transport Temperature
Refrigerated
Specimen Stability
Room temperature: 72 hours
Refrigerated: 28 days
Frozen: 28 days
Refrigerated: 28 days
Frozen: 28 days
Reject Criteria (Eg, hemolysis? Lipemia? Thaw/Other?)
Gross hemolysis
Methodology
NMO/AQP4-IgG Enzyme-Linked Immunosorbent Assay/Indirect Immunofluorescence
Setup Schedule
Monday through Friday; 8 a.m.
Report Available
Report available 2 to 3 days upon receipt at Mayo Medical Laboratories
Reference Range
NMO/AQP4-IgG: <1.6 U/mL
Clinical Significance
Establishing the diagnosis of an neuromyelitis optica spectrum disorder and distinguishing one of these disorders from multiple sclerosis early in the course of disease, allowing early initiation, and maintenance, of optimal therapy.
