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C. diff Quik Check Complete
Test CodeCDFQCK
Alias/See Also
C. diff, Clostridium difficile, c diff
CPT Codes
87324
Preferred Specimen
6 mL diarrheal (unformed) stool specimens
Minimum Volume
3 mL diarrheal (unformed) stool specimens
Transport Container
Sterile Leak proof container
Transport Temperature
Refrigerated
Specimen Stability
Room Temperature: Unacceptable
Refrigerated: 3 days
Frozen: 30 days at 10 C or lower
Refrigerated: 3 days
Frozen: 30 days at 10 C or lower
Reject Criteria (Eg, hemolysis? Lipemia? Thaw/Other?)
Formed stools, repeat samples during the same episode of diarrhea, Test of Cure, rectal swabs, preserved specimens.
Methodology
Immunochromatographic
Setup Schedule
Monday through Sunday
Report Available
Reports in 24 hours
Clinical Significance
After treatment with antibiotics, many patients develop gastrointestinal problems ranging from mild diarrhea to severe pseudomembranous colitis. Many cases of the milder forms of gastrointestinal illness, and most cases of pseudomembranous colitis, are caused by toxigenic strains of Clostridium difficile.
Clostridium difficile glutamate dehydrogenase is a good antigen marker in feces, because it is produced in high amounts by all strains, toxigenic or non-toxigenic. A positive result for glutamate dehydrogenase confirms the presence of this organism in a fecal specimen; a negative result indicates the absence of the organism. A positive result for toxins A/B confirms the presence of toxigenic Clostridium difficile. The C. DIFF QUIK CHEK COMPLET immunochromatographic cartridge assay determines the presence of both glutamate dehydrogenase and C. difficile toxins A and B as a primary screen for C. difficile infection.
Indeterminant results (GDH positive/toxin A/B negative) are confirmed by the BD MAX C. diff PCR assay. This two-step algorithm is a cost-effective method for highly sensitive detection of toxigenic Clostridium difficile.
Clostridium difficile glutamate dehydrogenase is a good antigen marker in feces, because it is produced in high amounts by all strains, toxigenic or non-toxigenic. A positive result for glutamate dehydrogenase confirms the presence of this organism in a fecal specimen; a negative result indicates the absence of the organism. A positive result for toxins A/B confirms the presence of toxigenic Clostridium difficile. The C. DIFF QUIK CHEK COMPLET immunochromatographic cartridge assay determines the presence of both glutamate dehydrogenase and C. difficile toxins A and B as a primary screen for C. difficile infection.
Indeterminant results (GDH positive/toxin A/B negative) are confirmed by the BD MAX C. diff PCR assay. This two-step algorithm is a cost-effective method for highly sensitive detection of toxigenic Clostridium difficile.
