Alkaline Phosphatase, Bone Specific

Test Code
ALKBS

Quest Code
29498

CPT Codes
84075

Specimen Container
No additive (red-top)

Preferred Specimen
1 mL serum (0.3 mL minimum)

Transport Temperature
Room temperature

Specimen Stability
Room temperature and Refrigerated: 7 days
Frozen: 60 days

Reject Criteria
Room temperature or refrigerated   Gross hemolysis

Methodology
Immunoenzymatic

Reference Range
mcg/L**FemalesMales
0 - 1 month:Not Established
2 - 24 months:25.4 - 124.025.4 - 124.0
25 months - 5 years:Not Established
6 - 9 years:41.0 - 134.641.0 - 134.6
10 - 13 years:24.2 - 154.243.8 - 177.4
14 - 17 years:10.5 - 75.213.7 - 128.0
18 - 29 years:4.7 - 17.88.4 - 29.3
30 - 39 years:5.3 - 19.57.7 - 21.3
40 - 49 years:5.0 - 18.87.0 - 18.3
50 - 68 years: 7.6 - 14.9
50 - 76 years:5.6 - 29.0 
Premenopausal females:  
35 - 45 years:5.0 - 18.2 
**Pediatric data from Int J Biol Markers (1996) 11:159-164


Clinical Use
This test is used for the therapeutic monitoring of postmenopausal osteoporosis and Paget's disease.

Performed By
Quest Diagnostics Nichols Institute