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Cortisol, Free, 24-Hour Urine with Creatinine, LC/MS/MS
Test CodeUCORT
Quest Code
11280
Alias/See Also
CORTISOL FR 24H U
CPT Codes
82530
Preferred Specimen
2 mL aliquot of an unpreserved 24-hour urine submitted in a plastic, leak-proof container
Minimum Volume
0.5 mL
Other Acceptable Specimens
Aliquot of a preserved 24-hour urine preserved in 25 mL 6N HCl, or 10 mL concentrated glacial acetic acid, or 10 grams boric acid
Instructions
Collect 24-hour urine without preservative (preferred). Record 24-hour urine volume on test request form and urine vial.
Transport Temperature
Refrigerated (cold packs)
Specimen Stability
Room temperature: 14 days
Refrigerated: 21 days
Frozen: 3 months
Refrigerated: 21 days
Frozen: 3 months
Methodology
Liquid Chromatography/Tandem Mass Spectrometry (LC/MS/MS)
Setup Schedule
Set up: Mon-Fri; Report available: 2-6 days
Reference Range
See Laboratory Report
Clinical Significance
Urinary Free Cortisol is useful in the detection of patients with Cushing's syndrome for whom Free Cortisol concentrations are elevated.
Performing Laboratory
Quest Diagnostics Nichols Institute San Juan Capistrano
33608 Ortega Highway
San Juan Capistrano, CA 92675