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Alpha-1-Antitrypsin, Quantitative
Test CodeA1A
Quest Code
235
Alias/See Also
ALPHA 1 ANTITRYPSIN QUANT
CPT Codes
82103
Preferred Specimen
1 mL serum from fasting patient
Minimum Volume
0.5 mL
Transport Temperature
Room temperature
Specimen Stability
Room temperature: 7 days
Refrigerated: 7 days
Frozen: 90 days
Refrigerated: 7 days
Frozen: 90 days
Methodology
Immunoturbidimetric Assay
Setup Schedule
Monday-Saturday Afternoon Report available: Next Day
Reference Range
83-199 mg/dL
Clinical Significance
Alpha-1-Antitrypsin level may be increased in normal pregnancy and in several diseases including chronic pulmonary disease; hereditary angioedema; renal, gastric, liver and pancreatic diseases; diabetes; carcinomas and rheumatoid diseases. Alpha-1-Antitrypsin may be decreased in emphysema, hepatic cirrhosis, respiratory distress syndrome of the newborn, nephrosis, malnutrition and cachexia. If a deficiency is present, aat phenotyping may be considered to confirm heterozygous versus homozygous deficiencies.
Performing Laboratory
Quest Diagnostics Nichols Institute
14225 Newbrook Drive
Chantilly, VA 20153