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Cryoglobulin and Cryofibrinogen Panel, Serum and Plasma
MessageThis test can only be drawn at Waldemere Medical Plaza -- Waldemere Lab Patients Only must arrive prior to 3 p.m. for collection.
Collection Instructions: Place tubes in container with prewarmed sand. Warm at 37° C for 1 hour before removing serum.
1. Tube must remain at 37 degrees C.
2. Allow blood to clot at 37 degrees C. (Serum only)
3. Centrifuge at 37 degrees C. Do not use a refrigerated centrifuge. If absolutely necessary, ambient temperature is acceptable. It is very important that the specimen remain at 37 degrees C until after separation of serum from red blood cells.
4. Place serum into an appropriately labeled plastic vial.
5. Refrigerate Serum immediately Additional Information: Analysis cannot be performed with less than 3 mL of serum. Smaller volumes are insufficient to detect clinically important trace (mixed) cryoglobulins. Less than 3 mL will require collection and submission a new specimen.
Collection Instructions: Place tubes in container with prewarmed sand. Warm at 37° C for 1 hour before removing serum.
1. Tube must remain at 37 degrees C.
2. Allow blood to clot at 37 degrees C. (Serum only)
3. Centrifuge at 37 degrees C. Do not use a refrigerated centrifuge. If absolutely necessary, ambient temperature is acceptable. It is very important that the specimen remain at 37 degrees C until after separation of serum from red blood cells.
4. Place serum into an appropriately labeled plastic vial.
5. Refrigerate Serum immediately Additional Information: Analysis cannot be performed with less than 3 mL of serum. Smaller volumes are insufficient to detect clinically important trace (mixed) cryoglobulins. Less than 3 mL will require collection and submission a new specimen.
Test Code
CRYOP
Includes
Cryoglobulin, Cryofibrinogen
If cryoglobulin has a positive result after 1 or 7 days, then immunofixation will be performed at an additional charge. Positive cryoglobulins of 0.1 mL or above of precipitate will be typed once.
If cryoglobulin has a positive result after 1 or 7 days, then immunofixation will be performed at an additional charge. Positive cryoglobulins of 0.1 mL or above of precipitate will be typed once.
Preferred Specimen
Serum (Red no Gel) AND
Plamsa (Lavendar Top)
Plamsa (Lavendar Top)
Minimum Volume
Plasma: 0.5 mL
Serum: 3 mL
Additional Information: Analysis cannot be performed with less than 3 mL of serum. Smaller volumes are insufficient to detect clinically important trace (mixed) cryoglobulins. Less than 3 mL will require collection and submission a new specimen.
Serum: 3 mL
Additional Information: Analysis cannot be performed with less than 3 mL of serum. Smaller volumes are insufficient to detect clinically important trace (mixed) cryoglobulins. Less than 3 mL will require collection and submission a new specimen.
Reject Criteria (Eg, hemolysis? Lipemia? Thaw/Other?)
Serum collected in SST Tube
Specimen not collected/held at 37°C prior to contrifugation
Specimen not collected/held at 37°C prior to contrifugation
Setup Schedule
Monday-Friday
Performing Laboratory
Mayo Clinic Laboratories
Additional Information
Specimen Requirements
