|
|
| A B C D E F G H I J K L M N O P Q R S T U V W X Y Z # |
Pneumocystis Jirovecii DNA Qnt
Test CodePNEU JIROV
Alias/See Also
PNEUMOJIR
CPT Codes
87799
Preferred Specimen
1 mL bronchoalveolar lavage (BAL) or bronchial wash submitted in a sterile leak-proof container
Minimum Volume
1
Instructions
0.7 ml bronchial lavage/wash submitted in leakproof containe
Transport Container
MISC
Transport Temperature
R
Specimen Stability
Room temperature: 48 hours
Refrigerated: 7 days
Frozen: 30 days
Refrigerated: 7 days
Frozen: 30 days
Methodology
Real-Time Polymerase Chain Reaction (PCR)
Setup Schedule
Set up: Mon-Sat; Report available: 2-3 days
Reference Range
| P. jirovecii DNA, QN PCR | Not Detected (copies/mL) |
| P. jirovecii DNA, QN PCR | Not Detected (Log copies/mL) |
Clinical Significance
This test is intended for HIV-positive and immunocompromised individuals with clinical presentation and/or radiographic findings consistent with P. jirovecii infection. This test can be used to aid in the diagnosis of P. jirovecii pneumonia (PCP) enabling the initiation of specific therapy. The PCR test has higher sensitivity and specificity when compared to alternative diagnostic methods such as staining (GMS, Calcofluor white, DFA), (1,3) β-D-glucan test or imaging studies. Due to the analytical sensitivity of this assay, the test can be positive in colonized individuals without clinical evidence of PCP. The reportable range of this test is 250 to 125,000,000 copies/mL (2.40 to 8.10 Log copies/mL). The results of this test should be interpreted in the context of pertinent clinical findings and history.
Reference
1. Bateman M, et al. Medical Mycology. 2020;58 :1015-1028.
Reference
1. Bateman M, et al. Medical Mycology. 2020;58 :1015-1028.
Performing Laboratory
| Quest Diagnostics Nichols Institute-San Juan Capistrano, CA |
| 33608 Ortega Highway |
| San Juan Capistrano, CA 92675-2042 |
