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A B C D E F G H I J K L M N O P Q R S T U V W X Y Z # |
Lupus Anticoag Eval Reflx 7079
Test CodeAlias/See Also
CPT Codes
85613;85730
Includes
Preferred Specimen
Minimum Volume
Instructions
Transport Container
Transport Temperature
Specimen Stability
Refrigerated: Unacceptable
Frozen: 30 days
Reject Criteria (Eg, hemolysis? Lipemia? Thaw/Other?)
Methodology
Clot detection
Setup Schedule
Limitations
Reference Range
Lupus Anticoagulant | Not detected |
PTT-LA Screen | ≤40 sec |
dRVVT Screen | ≤45 sec |
Clinical Significance
Lupus anticoagulants (LA) are members of a family of antibodies with phospholipid-protein specificity. LA may be defined as an immunoglobulin, IgG or IgM or a mixture of both, that interferes with one or more of the in-vitro phospholipid (PL) dependent tests of coagulation. These antibodies are not associated with a hemorrhagic diathesis, but rather have been linked to thrombotic events. In addition to thrombosis other clinical complications have been associated with the presence of LA. These include strokes, nonbacterial thrombotic endocarditis, livedo reticularis and a variety of obstetrical complications such as intrauterine fetal death, recurrent spontaneous abortion, fetal growth retardation, early onset preeclampsia and chorea gravidarum.
Note: Target specific anticoagulant therapy (anti-Xa medications, direct thrombin inhibitors) may cause false positive results.
Performing Laboratory
Quest Diagnostics Nichols Institute |
14225 Newbrook Drive |
Chantilly, VA 20153 |