ANCA SC MPO PR3 RF ANCA 70159X

Test Code
ANCA-PAN


Alias/See Also
ANCA-PAN


CPT Codes
86021 X 3

Includes
ANCA screen reflex titers; Myeloperoxidase Antibody, Proteinase 3 antibody; Saccharomyces cerevisiae Antibody


Preferred Specimen
2 mL serum collected in a red-top tube (no gel)


Minimum Volume
1


Instructions
Draw one red top tube (no gel) and send serum refrigerated


Transport Container
RED


Transport Temperature
R


Specimen Stability
Room temperature: 7 days
Refrigerated: 14 days
Frozen: 30 days


Reject Criteria (Eg, hemolysis? Lipemia? Thaw/Other?)
Gross hemolysis • Grossly lipemic


Methodology
Immunoassay (IA)

Setup Schedule
Set up: Mon-Sat p.m.; Report available: 3-5 days


Reference Range
ANCA Screen Negative
  P-ANCA Titer <1:20
  C-ANCA Titer <1:20
  Atypical P-ANCA Titer <1:20

Myeloperoxidase Antibody
<1.0 AI No antibody detected
≥1.0 AI Antibody detected

Proteinase-3 Antibody
<1.0 AI No antibody detected
≥1.0 AI Antibody detected


Clinical Significance
Testing for anti-neutrophil cytoplasmic antibodies (P-ANCA and/or C-ANCA) has been found to be useful in establishing the diagnosis of suspected vascular diseases, inflammatory bowel disease, as well as other autoimmune diseases.


Performing Laboratory
Quest Diagnostics Nichols Institute
14225 Newbrook Drive
Chantilly, VA 20153



The CPT Codes provided in this document are based on AMA guidelines and are for informational purposes only. CPT coding is the sole responsibility of the billing party. Please direct any questions regarding coding to the payor being billed. Any Profile/panel component may be ordered separately. Reflex tests are performed at an additional charge.