Liver Fibrosis Panel 92688

Test Code
LIVFIBR


Alias/See Also
LIVFIBR


CPT Codes
82172;82247;82977;83010;83883;84460

Includes
ALT, GGT, Alpha-2-Macroglobin;Apolipoprotein A1; Bilirubin;Haptoglobin, Fibrosis Score, Necroinflam Act Score


Preferred Specimen
3.5 mL serum


Patient Preparation
Overnight fasting is preferred

Minimum Volume
2


Instructions
Overnight fasting. Collect 2 SST, spin ASAP, and send serum frozen.


Transport Container
SST


Transport Temperature
F


Specimen Stability
Room temperature: 24 hours
Refrigerated: 72 hours
Frozen -20° C: 5 days
Frozen -70° C: 28 days


Reject Criteria (Eg, hemolysis? Lipemia? Thaw/Other?)
Gross hemolysis • Grossly lipemic • Patients <2 years old • QNS for one or more analytes


Methodology
Nephelometry • Spectrophotometry (SP)

FDA Status
This test was developed and its analytical performance characteristics have been determined by Quest Diagnostics. It has not been cleared or approved by the U.S. Food and Drug Administration. This assay has been validated pursuant to the CLIA regulations and is used for clinical purposes.

Setup Schedule
Set up: Mon-Sat; Report available: 2-5 days


Reference Range
See Laboratory Report


Clinical Significance
FibroTest and ActiTest permit the non-invasive evaluation of Hepatitis C (or B) individuals for the presence of liver fibrosis and liver inflammation, respectively. The FibroTest and ActiTest scores are calculated based on patient age, gender and concentrations of serum of y-glutamyl transferase (GGT), total bilirubin (TB), a-2 macroglobulin, haptoglobin, apolipoprotein A1 and alanine aminotransferase (ActiTest). Fibrotest and ActiTest Scores, on a scale of 0.0 to 1.0, are assigned a Metavir scale indicating the level of fibrosis or inflammation present.


Performing Laboratory
Quest Diagnostics Nichols Institute-San Juan Capistrano, CA
33608 Ortega Highway
San Juan Capistrano, CA 92675-2042




The CPT Codes provided in this document are based on AMA guidelines and are for informational purposes only. CPT coding is the sole responsibility of the billing party. Please direct any questions regarding coding to the payor being billed. Any Profile/panel component may be ordered separately. Reflex tests are performed at an additional charge.