Vitamin K [36585X]

Test Code
VITK

CPT Codes
84597

Preferred Specimen
3 mL plasma collected in an EDTA (lavender-top) tube

Minimum Volume
1.5 mL

Other Acceptable Specimens
Plasma collected in: Lithium heparin (green-top) tube

Instructions
Separate and freeze immediately in plastic screw-cap vial. Wrap sample in foil before sending to lab. No disclaimer is required.

Note: Samples received frozen but not protected from light are acceptable. Samples received refrigerated but not protected from light are unaccpetable and should be rejected.

Transport Container
Plastic screw-cap vial protected from light

Transport Temperature
Frozen

Specimen Stability
Room temperature: Unacceptable
Refrigerated: Unacceptable
Frozen: 90 days

Reject Criteria (Eg, hemolysis? Lipemia? Thaw/Other?)
Received room temperature • Received refrigerated • Serum

Methodology
High Performance Liquid Chromatography (HPLC)

Setup Schedule
Set up: Tues a.m.; Report available: 2 days

Reference Range
80-1160 pg/mL

Clinical Significance
Vitamin K is a required co-factor for the synthesis of factors 2, 7, 9, and 10 and proteins C and S. Deficiencies of vitamin K lead to bleeding. Coumadin® (warfarin) acts as an anticoagulant because it is a vitamin K antagonist.

Performed By
Quest Diagnostics Nichols Institute



The CPT Codes provided in this document are based on AMA guidelines and are for informational purposes only. CPT coding is the sole responsibility of the billing party. Please direct any questions regarding coding to the payor being billed. Any Profile/panel component may be ordered separately. Reflex tests are performed at an additional charge.