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RAPID PLASMA REAGIN (RPR)

Test Code
Lab5102


Alias/See Also
RPR


CPT Codes
86592

Preferred Specimen
Serum


Minimum Volume
2 mL, 0.5-1 mL for neonates.


Instructions

Centrifuge SST after clotting to separate serum from cells




Transport Container

Serum separator tube – SST (serum)




Transport Temperature
Room temperature


Specimen Stability

Refrigerated – 5 days (after specimen separation)




Reject Criteria (Eg, hemolysis? Lipemia? Thaw/Other?)
none


Methodology

RPR Card antigen suspension is a carbon particle cardiolipin antigen1 which detects “reagin”, an antibody-like substance present in serum or plasma from syphilitic persons, and occasionally in serum or plasma of persons with other acute or chronic conditions. The reagin binds to the test antigen, which consists of cardiolipin-lecithin-coated cholesterol particles, causing macroscopic flocculation.

 



Setup Schedule
Daily


Reference Range
Non-reactive


Clinical Significance

RPR is a non-treponemal testing procedure for the serologic detection of syphilis.




Performing Laboratory
Meritus Immunology – Microbiology



The CPT Codes provided in this document are based on AMA guidelines and are for informational purposes only. CPT coding is the sole responsibility of the billing party. Please direct any questions regarding coding to the payor being billed. Any Profile/panel component may be ordered separately. Reflex tests are performed at an additional charge.