Alpha-1-Antitrypsin (AAT) Mutation Analysis [15340X]

Test Code
A1AP

CPT Codes
81332

Preferred Specimen
5 mL whole blood (minimum 3 mL)

Minimum Volume
2 mL

Other Acceptable Specimens
Whole blood collected in: EDTA (royal blue-top), sodium heparin (green-top), lithium heparin (green-top), ACD solution B (yellow-top) or ACD solution A (yellow-top) tube

Instructions
Whole Blood: Use normal phlebotomy procedure. Do not transfer to other containers. Specimen stability is crucial. Store and ship ambient immediately. Do not freeze WB specimens.



Extracted DNA:
Please call 1-866-GENE-INFO (1-866-436-3463) for additional information.

Transport Container
EDTA (lavender top)

Transport Temperature

Room temperature



Specimen Stability
Room temperature: 8 days

Refrigerated: 8 days

Frozen: Unacceptable

Reject Criteria (Eg, hemolysis? Lipemia? Thaw/Other?)
Received frozen

Methodology
Fluorescent Restriction Fragment Length Polymorphism

This test was developed and its performance characteristics have been determined by Quest Diagnostics. Performance characteristics refer to the analytical performance of the test.

Limitations
Rare alleles (other than S and Z types) are not tested for by this assay.

Reference Range
Accompanies report

Clinical Significance
Individuals who carry two copies (homozygous) for the Z
allele are at a higher risk to develop liver disease and
emphysema.

Performed By
Quest Diagnostics Nichols Institute



The CPT Codes provided in this document are based on AMA guidelines and are for informational purposes only. CPT coding is the sole responsibility of the billing party. Please direct any questions regarding coding to the payor being billed. Any Profile/panel component may be ordered separately. Reflex tests are performed at an additional charge.