Vitamin B2 (Riboflavin), Plasma

Test Code

CPT Codes


This test is not available for New York patient testing.

Preferred Specimen
2 mL plasma collected in an EDTA (lavender-top) tube

Minimum Volume
0.5 mL

Separate plasma and transfer to a plastic shipping vial to prevent breakage. Wrap tube in aluminum foil to protect from light. Freeze immediately.
Note: Samples received frozen but not protected from light are acceptable. Wrap sample in foil before sending to lab, no disclaimer is required. Samples received refrigerated but not protected from light are unacceptable and should be rejected.

Transport Container
Foil wrapped plastic screw-cap vial

Transport Temperature

Specimen Stability
Room temperature: 4 hours
Refrigerated: 24 hours
Frozen: 30 days

Reject Criteria (Eg, hemolysis? Lipemia? Thaw/Other?)
Received room temperature • Received refrigerated • Received refrigerated and not protected from light

Fluorometric Detection • High Performance Liquid Chromatography (HPLC)

Reference Range
6.2-39.0 nmol/L

Clinical Significance
Vitamin B2 is involved in metabolism of fats, carbohydrates, and protein. The clinical manifestations of deficiency are non-specific. Clinical manifestations include mucocutaneous lesions of the mouth and skin, corneal vascularization, anemia, and personality changes.

Performed By
Quest Diagnostics Nichols Institute

The CPT Codes provided in this document are based on AMA guidelines and are for informational purposes only. CPT coding is the sole responsibility of the billing party. Please direct any questions regarding coding to the payor being billed. Any Profile/panel component may be ordered separately. Reflex tests are performed at an additional charge.