Valproic Acid, Free [3314X]

Test Code

CPT Codes

Preferred Specimen
3 mL serum collected in a red-top tube (no gel)

Minimum Volume
1 mL

Other Acceptable Specimens
Serum collected in no additive (royal blue-top) tube • Plasma collected in an EDTA (lavender-top) or EDTA (royal blue-top) tube


Do not use gel barrier tubes. Collect as a trough just before next dose. Centrifuge and immediately separate serum or plasma specimens from the cells into clean, plastic, screw-capped vial(s). Transport refrigerated (cold packs).

Transport Container
Plastic screw-cap vial

Transport Temperature
Refrigerated (cold packs)

Specimen Stability
Room temperature: 48 hours

Refrigerated: 7 days

Frozen: 30 days

Reject Criteria (Eg, hemolysis? Lipemia? Thaw/Other?)
Serum separator tube (SST®)

Fluorescence Polarization Immunoassay (FPIA)

Clinical Significance
Valproic acid is a broad spectrum anticonvulsant for the treatment of absence seizures. It is effective in the management of generalized tonic-econic and myoconic seizures, as well as grand mal and petit mal.

Performed By
Quest Diagnostics Nichols Institute

The CPT Codes provided in this document are based on AMA guidelines and are for informational purposes only. CPT coding is the sole responsibility of the billing party. Please direct any questions regarding coding to the payor being billed. Any Profile/panel component may be ordered separately. Reflex tests are performed at an additional charge.