Vitamin A (Retinol)

Test Code
VITA

CPT Codes
84590

Preferred Specimen
2 mL serum

Minimum Volume
0.5 mL

Instructions

Centrifuge serum specimen within 1 hour of collection. Transfer serum to plastic, amber vial. If amber vial is not available, wrap tube in aluminum foil to protect from light. Refrigerate and send refrigerated (cold packs) or freeze -80°C and ship frozen on dry ice.



Transport Container
Plastic screw-cap vial protected from light

Transport Temperature
Refrigerated (cold packs)

Specimen Stability
Room Temperature: 24 hours
Refrigerated: 7 days
Frozen: 1 Year

Reject Criteria (Eg, hemolysis? Lipemia? Thaw/Other?)
Received unfrozen and unprotected from light • Frozen unprotected from light • Plasma

Methodology
High Performance Liquid Chromatography (HPLC)

Limitations
Results may be elevated in women on oral contraceptives.

Reference Range
1-6  Years 20-43 µg/dL 
7-12 Years 26-49 µg/dL 
13-19 Years    26-72 µg/dL 
Adults 38-98 µg/dL 


Clinical Significance
Vitamin A is critical for vision, growth, and many cell functions. High concentrations of vitamin A are seen with renal failure, but this is not associated with toxicity, and excessive ingestion. High concentrations are associated with bone fractures. Low concentrations of vitamin A are consistent with fat malabsorption and rarely due to inadequate diet. Vitamin A, vitamin E, and carotene are always extracted and detected simultaneously. This is a free vitamin A (retinol).

Performed By
Quest Diagnostics Nichols Institute



The CPT Codes provided in this document are based on AMA guidelines and are for informational purposes only. CPT coding is the sole responsibility of the billing party. Please direct any questions regarding coding to the payor being billed. Any Profile/panel component may be ordered separately. Reflex tests are performed at an additional charge.