Chromosome Analysis, Amniotic Fluid

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Testing performed by Integrated Genetics
Note: Call CoxHealth Laboratories at 417-269-7820 to obtain more specific information. 


Test Code
3982222


CPT Codes
88235 x 2-Tissue culture; 88267-Chromosome analysis, one karyotype; 88280-Chromosome analysis, additional karyotypes; 88291-Interpretation and report

Preferred Specimen
Sterile vial(s)


Minimum Volume
15 mL to 25 mL of amniotic fluid in 2 to 3 sterile vials.


Instructions
Discard first 2 mL of amniotic fluid to reduce the chance of maternal cell contamination. Do not centrifuge for any reason.
Note:
1. The following information is required:
     A. First day of last menstrual period
     B. Date ultrasound performed
     C. Gestational age by ultrasound
     D. Collection date
2. Gestational age must be between 15 and 17 weeks.


Transport Temperature
Ambient


Methodology
Banding-GTG banding, other banding methods are necessary
Computer imaging and computer-assisted karyotyping
Culture-a minimum of 2, usually 3, in situ cultures and a back-up flask culture



Limitations
 


Reference Range
An interpretive report will be provided.
All abnormal results will be called to the referring physician’s office by a board certified geneticist or a designated counseling staff member.


Performed By
CoxHealth



The CPT Codes provided in this document are based on AMA guidelines and are for informational purposes only. CPT coding is the sole responsibility of the billing party. Please direct any questions regarding coding to the payor being billed. Any Profile/panel component may be ordered separately. Reflex tests are performed at an additional charge.