Immunoperoxidase Studies, Tissue

3941155

Surgical pathology container(s) with 10% formalin, surgical towel, or dry container(s)

Specimen Volume: Tissue
Forms: Surgical Pathology Request Form
Collection Instructions:
1. Biopsy of primary or metastatic tumor submitted in a surgical pathology container with 10% formalin or a fresh specimen in a surgical towel or dry container.
2. Label container with patient’s full name (first and last), room number, hospital number, date of collection, and specimen source.
3. Notify histology technician or pathologist that specimen has been brought to Surgical Pathology Laboratory. 

Frozen

Monday through Friday

An interpretive report will be provided.

This immunoperoxidase technique (PAP) is used to localize antigens in tissue sections. It allows pathologists to examine the presence of specific cell products or extracellular material. The major applications of the method include: identification of the cell of origin of an antigen (ie, endocrine neoplasms), abnormal distribution or number of cells producing an antigen in a lesion (ie, hyperplasia or hypoplasia of endocrine cells), loss of normal antigen in a neoplasm (ie, blood group antigens in bladder and breast neoplasms), identification of oncofetal antigens in neoplasms (ie, alpha-fetoprotein [AFP], carcinoembryonic antigen [CEA]), histogenesis of lesions (ie, identification of tissue-specific markers in soft tissue neoplasms), detection of microorganisms, and detection of autoantibodies.