Maturation Index

Test Code
9548


CPT Codes
88155

Minimum Volume


Container/Tube: Slides
Specimen Volume: Smears
Forms: Cytology Request Form
Collection Instructions:
  
1. Using a lead pencil, label frosted end of a glass slide with patient’s name and lateral vaginal wall if accompanying Pap smear. Observe Universal Precautions for collecting and handling specimen.
   2. Use a cotton swab or scrape lateral vaginal wall; immediately roll across a clean, dry, frosted slide; and immediately fix with cytology fixative.
   3. Place slide in a plastic slide holder.
Note: 1. The following specimens will be returned to submitting physician:
A. No requisition form
B. Name on requisition does not match name on specimen
C. Broken slide that cannot be reconstructed
D. Unlabeled specimen
E. No doctor’s name given
F. Fixation in formalin
G. Air-drying artifact
H. Specimen taken from other than vaginal wall
I. Presence of inflammatory changes
2. Label holder with patient’s full name (first and last), date of collection, physician’s name, and hospital identification number (if applicable). 




Transport Temperature
Ambient


Methodology
Papanicolaou Stain Includes count of not <200 cells.

Setup Schedule
Monday through Saturday


Reference Range
Results reported in percentages, ie, 0/70/30, indicating 0% parabasal, 70% intermediate, and 30% superficial cells.
Interpretation depends on individual clinical situation. For specific questions of interpretation, call the CoxHealth Cytology Laboratory.
At birth (1st month): variability slight-MI 0/95/5
Childhood (about 8 years): variability moderate-MI 90/10/0
Perimenarche: variability great-MI 30/50/20
Childbearing age
  Ovulation: variability moderate-MI 0/40/60
  Menstruation: variability moderate-MI 0/70/30
  Pregnancy: variability slight-MI 0/95/5
  Postpartum: variability slight-MI 90/10/0
  Perimenopausal: variability great-MI 30/50/20
After childbearing age
  Postmenopausal: variability slight-MI 0/100/0
  Teleatrophy: variability moderate-100/0/0


Clinical Significance
Useful for evaluation of cellular composition of the surface layers of vaginal squamous epithelium, which reflects balance of estrogen and progesterone effects upon this target tissue. It is also useful in the diagnosis of conditions producing abnormal cytohormonal balance, ie, pituitary dysfunction, ovarian dysfunction, feminizing tumor, and virilizing tumor.  


Performed By
CoxHealth



The CPT Codes provided in this document are based on AMA guidelines and are for informational purposes only. CPT coding is the sole responsibility of the billing party. Please direct any questions regarding coding to the payor being billed. Any Profile/panel component may be ordered separately. Reflex tests are performed at an additional charge.