Cortisol, Free, 24-Hour Urine [11280X]

Test Code

CPT Codes


Preferred Specimen
2 mL aliquot of an unpreserved 24-hour urine

Minimum Volume
0.8 mL

Other Acceptable Specimens
Aliquot of a preserved 24-hour urine

Collect 24-hour urine without preservative (preferred). Record 24-hour urine volume on test request form and urine vial.

24-hour urine specimens, collected with the following preservatives, are acceptable:
25 mL 6N HCl; 10 mL conc. Glacial Acetic Acid; 10 g Boric Acid

Transport Container
Urine Container, leak-proof

Transport Temperature
Refrigerated (cold packs)

Specimen Stability
Room temperature: 48 hours
Refrigerated: 7 days
Frozen: 5 months

Liquid Chromatography, Tandem Mass Spectrometry (LC/MS/MS)

Reference Range
See Laboratory Report

Clinical Significance
Urinary Free Cortisol is useful in the detection of patients with Cushing's syndrome for whom Free Cortisol concentrations are elevated.

Performing Laboratory
Quest Diagnostics Nichols Institute San Juan Capistrano
33608 Ortega Highway
San Juan Capistrano, CA 92675

The CPT Codes provided in this document are based on AMA guidelines and are for informational purposes only. CPT coding is the sole responsibility of the billing party. Please direct any questions regarding coding to the payor being billed. Any Profile/panel component may be ordered separately. Reflex tests are performed at an additional charge.