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Cryoglobulin Qualitative Analysis [383X]Test Code
5 mL Serum
After collection, allow specimen to clot at 37° C for 30-60 minutes. Place tube in a 37° C incubator or a waterbath. If not available, adjust tap water in a container to 37° C. Place collection tube into the container. Monitor temperature throughout clotting process. Centrifuge clotted tube in a pre-warmed centrifuge (run the centrifuge for 10 minutes prior to centrifuging the specimen). Pour serum into a plastic screw-capped vial and submit at room temperature.
Plastic screw-cap vial
Room temperature: 3 days
Reject Criteria (Eg, hemolysis? Lipemia? Thaw/Other?)
Gross hemolysis • Received frozen • Received refrigerated • Serum Separator Tube (SST®)
Cryoglobulins are a group of proteins which precipitate from serum, plasma or urine upon exposure to cold.
Quest Diagnostics Nichols Institute