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A B C D E F G H I J K L M N O P Q R S T U V W X Y Z # |
Actin (Smooth Muscle) Antibody (IgG)
Test CodeACTINAB
CPT Codes
86015
Preferred Specimen
0.5 mL serum
Minimum Volume
0.25 mL
Transport Container
Plastic screw-cap vial
Transport Temperature
Room temperature
Specimen Stability
Room temperature: 14 days
Refrigerated: 14 days
Frozen: 30 days
Refrigerated: 14 days
Frozen: 30 days
Reject Criteria (Eg, hemolysis? Lipemia? Thaw/Other?)
Gross hemolysis • Lipemia • Microbially contaminated serum • Specimens containing heavy, visible particulate
Methodology
Enzyme Linked Immunosorbent Immunoassay (ELISA)
Setup Schedule
Set up: Tues-Sat; Report available: Next day
Clinical Significance
Actin is the major antigen to which smooth muscle antibodies react in autoimmune hepatitis. F-Actin IGG antibodies are found in 52-85% of patients with Autoimmune Hepatitis (AIH) or chronic active hepatitis and in 22% of patients with Primary Biliary Cirrhosis (PBC). Anti-Actin antibodies have been reported in 3-18% of sera from normal healthy controls.
Performing Laboratory
Quest Diagnostics Nichols Institute |
14225 Newbrook Drive |
Chantilly, VA 20153 |